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Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake...

The review goes from Cannabis sativa and its hundreds of bioactive compounds to Δ9-tetrahydrocannabinol (THC) and mainly cannabidiol (CBD)...

Besides, several studies have described CBD as a multitarget molecule, acting as an adaptogen and as a...

At low concentrations (sub-micromolar scale), CBD binds to equilibrative nucleoside transporter (ENT), transient receptor potential melastatin type 8 (TRPM8), serotonin 1A receptor (5-HT1A), glycine...

The review goes from Cannabis sativa and its hundreds of bioactive compounds to Δ9-tetrahydrocannabinol (THC) and...

On the other hand, daily administration of CBD (3 mg/kg) for 14 days decreased both dopamine depletion...

Besides, several studies have described CBD as a multitarget molecule, acting as an adaptogen and as a modulator, in different ways,...

Therefore, double-blind, placebo-controlled, randomized trials with larger samples of patients with PD are needed to elucidate the possible effectiveness and mechanisms involved in the therapeutic...

An open-label pilot study conducted in PD patients showed that oral doses of CBD ranging from 150-400 mg/day, combined with...

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